Lexicon to Present at Biotech Industry Conference

THE WOODLANDS, Texas -- Lexicon Pharmaceuticals, Inc. (Nasdaq:LXRX) has announced that a member of Lexicon senior management will present at the Future Leaders in the Biotech Industry Conference at the Millennium Broadway Hotel in New York, New York on Thursday, March 27, 2008 at 9:30 a.m. Eastern Time.

A live webcast of Lexicon's presentation may be accessed on its corporate Web site. An archived version of the webcast will be available on the website through April 4, 2008.

About Lexicon 
Lexicon is a biopharmaceutical company focused on the discovery and development of breakthrough treatments for human disease. Lexicon currently has development programs underway for such areas of major unmet medical need as irritable bowel syndrome, cognitive disorders, autoimmune diseases, and carcinoid syndrome. The company has used its proprietary gene knockout technology to discover more than 100 promising drug targets and create an extensive pipeline of clinical and preclinical programs in the therapeutic areas of cardiology, gastroenterology, immunology and oncology, metabolism, neurology and ophthalmology. To advance the development and commercialization of its programs, Lexicon is working both independently and through collaborators including Bristol-Myers Squibb Co., Genentech, Inc. and N.V. Organon. For additional information about Lexicon and its programs, please visit their Web site.