St. Luke's Health Announces Houston Chief Medical Officer

HOUSTON, TX -- St. Luke’s Health, a member of CommonSpirit, today announced the appointment of Augusto “Gus” Sepulveda, MD, MPH, FACP, as the new chief medical officer (CMO) for Houston Market and Baylor St. Luke's Medical Center, effective March 2, 2026.

Dr. Sepulveda brings 28 years of health care experience with a strong background in physician leadership, academic medicine and clinical operations. He joins St. Luke’s from HCA Houston Healthcare Kingwood, where he has served as CMO since May 2025.

Prior to his role in Kingwood, Dr. Sepulveda held the position of CMO for HCA Healthcare’s West Florida Division. In this capacity, he was responsible for overseeing clinical quality, patient safety and performance improvement across a comprehensive network comprising 17 hospitals, more than 30 emergency rooms, 13 surgery centers and numerous other facilities. His experience also includes leadership roles as associate CMO for HCA Healthcare Gulf Coast Division, and as CMO at both HCA Houston Healthcare Northwest and HCA Houston Healthcare Tomball.

“Dr. Sepulveda’s commitment to clinical excellence and patient care is in perfect alignment with CommonSpirit's mission,” said Simon Payne, MD, MBA, chief medical officer for CommonSpirit’s South Region.“We are confident that his leadership will be a significant asset to the communities we serve in our Houston market.”

Dr. Sepulveda is board-certified in internal medicine and clinical informatics. He holds a master of public health degree and a medical doctor degree from Ponce Health Sciences University, and completed his residency at Hospital Damas, where he served as chief resident.